AIM The authors conducted two cross-sectional studies 8 years apart with the aim of assessing temporal trends in the prevalence of asthma and atopic diseases in Međimurje County, Northwestern Croatia. METHODS Studies were conducted in children aged 12 years 0 months to 14 years 11 months in 2005 and in 2013; additionally, in adolescents aged 18 years in 2013 according to the international study on asthma and allergies protocol. RESULTS In the age group 12-14 years, a significant increase in the prevalence of asthma (5.1% vs 8.31%), allergic rhinitis (10.86% vs 16.24%), allergic rhinoconjunctivitis (7.14% vs 10.95%) and atopic dermatitis (5.34% vs 8.12%) was observed. When the age group 12-14 years in 2005 was compared with the age group 18 years in 2013, a significant increase in symptoms of asthma (5.1% vs 11.5%), allergic rhinitis (10.86% vs 19.59%), allergic rhinoconjunctivitis (7.14% vs 14.25%), and atopic dermatitis (5.34% vs 7.69%) was observed. CONCLUSION This study shows an increasing trend in Međimurje County in the prevalence of all symptoms associated with atopic diseases: Asthma, allergic rhinitis, allergic rhinoconjunctivitis, and atopic dermatitis.

中文翻译：

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克罗地亚-ISAAC III 期（2013 年）西北部哮喘和特应性疾病的时间趋势。

目的 作者进行了两次相隔 8 年的横断面研究，旨在评估克罗地亚西北部 Međimurje 县哮喘和特应性疾病患病率的时间趋势。方法 在 2005 年和 2013 年对 12 岁 0 个月至 14 岁 11 个月的儿童进行研究；此外，根据国际哮喘和过敏研究方案，2013 年 18 岁的青少年。结果 在 12-14 岁年龄段，哮喘（5.1% vs 8.31%）、过敏性鼻炎（10.86% vs 16.24%）、过敏性鼻结膜炎（7.14% vs 10.95%）和特应性皮炎（5.34 % 对 8.12%) 被观察到。2005 年 12-14 岁年龄组与 2013 年 18 岁年龄组相比，哮喘症状显着增加（5.1% vs 11.5%）、过敏性鼻炎（10. 观察到 86% vs 19.59%)、过敏性鼻结膜炎 (7.14% vs 14.25%) 和特应性皮炎 (5.34% vs 7.69%)。结论 本研究显示，在 Međimurje 县，与特应性疾病相关的所有症状的患病率呈上升趋势：哮喘、过敏性鼻炎、过敏性鼻结膜炎和特应性皮炎。