Large Clostridial Toxins: Mechanisms and Roles in Disease,Microbiology and Molecular Biology Reviews

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Large Clostridial Toxins: Mechanisms and Roles in Disease
Microbiology and Molecular Biology Reviews ( IF 12.9 ) Pub Date : 2021-06-02 , DOI: 10.1128/mmbr.00064-21
Kathleen E Orrell _{1,

2} , Roman A Melnyk _{1,

2}

Affiliation

Large clostridial toxins (LCTs) are a family of bacterial exotoxins that infiltrate and destroy target cells. Members of the LCT family include Clostridioides difficile toxins TcdA and TcdB, Paeniclostridium sordellii toxins TcsL and TcsH, Clostridium ...

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