Be Under Your Own Influence (BUYOI) is a previously validated school-based intervention designed to delay adolescent substance use (SU) initiation. This study examined the effectiveness of a culturally-adapted version of BUYOI in delaying SU initiation among reservation-dwelling American Indian (AI) youth. Five reservation-based middle schools participated. Three schools were randomly assigned to receive BUYOI-AI (N = 321), and two schools served as controls (N = 176). Beginning in 7th grade, all participating students completed four assessments over the study period. Discrete time hazard models estimated the effects of BUYOI on students’ risk of initiating alcohol, alcohol intoxication and marijuana before the end of 8th grade. AI students exposed to BUYOI had a lower risk of initiating alcohol use or intoxication, though sex moderated the effect on intoxication. These findings provide preliminary support for the effectiveness of a culturally-adapted version of BUYOI in delaying AI youth's first-time alcohol use and intoxication.

中文翻译：

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受自己的影响：针对居住在保留地的美国印第安青年的文化适应药物预防运动的有效性

受到自己的影响 (BUYOI) 是一项先前经过验证的基于学校的干预措施，旨在延迟青少年物质使用 (SU) 的开始。本研究检验了文化适应版本的 BUYOI 在延迟居住在保留地的美洲印第安人 (AI) 青年的 SU 启动方面的有效性。五所预约制中学参加。三所学校被随机分配接受BUYOI-AI（N  = 321），两所学校作为对照（N = 176)。从 7 年级开始，所有参与的学生在学习期间完成了四次评估。离散时间风险模型估计了 BUYOI 对学生在 8 年级结束前开始饮酒、酒精中毒和吸食大麻的风险的影响。接触 BUYOI 的 AI 学生开始使用酒精或中毒的风险较低，尽管性降低了对中毒的影响。这些发现为文化适应版本的 BUYOI 在延迟 AI 青年首次饮酒和中毒方面的有效性提供了初步支持。