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Validation of the ICH score and ICH-GS in a Peruvian surgical cohort: a retrospective study
Neurosurgical Review ( IF 2.8 ) Pub Date : 2021-07-18 , DOI: 10.1007/s10143-021-01605-2
Aaron Rodriguez-Calienes 1, 2 , Marco Malaga 1, 2 , Carlos Alva-Diaz 2, 3 , Giancarlo Saal-Zapata 4, 5
Affiliation  

The intracerebral hemorrhage (ICH) score and the ICH-grading scale (ICH-GS) are mortality predictor tools developed predominantly in conservatively treated ICH cohorts. We aimed to compare and evaluate the external validity of both models in predicting mortality in patients with ICH undergoing surgical intervention. A retrospective review of all patients presenting with spontaneous ICH admitted to a Peruvian national hospital between January 2018 and March 2020 was conducted. We compared the area under the receiver operating characteristic curve (AUC) for the ICH score and ICH-GS for in-hospital, 30-day, and 6-month mortality prediction. The research protocol was approved by the Institutional Review Board. A total of 73 patients (median age 62 years, 56.2% males) were included in the study. The mean ICH and ICH-GS scores were 2.5 and 8.7, respectively. In-hospital, 30-day, and 6-month mortality were 37%, 27.4%, and 37%, respectively. The AUC for in-hospital, 30-day, and 6-month mortality was 0.69, 0.71, and 0.69, respectively, for the ICH score and 0.64, 0.65, and 0.68, respectively, for the ICH-GS score. In this study, the ICH score and ICH-GS had moderate discrimination capacities to predict in-hospital, 30-day, and 6-month mortality in surgically treated patients. Additional studies should assess whether surgical intervention affects the discrimination of these prognostic models in order to develop predictive scores based on specific populations.



中文翻译:

在秘鲁手术队列中验证 ICH 评分和 ICH-GS:一项回顾性研究

脑出血 (ICH) 评分和 ICH 分级量表 (ICH-GS) 是主要在保守治疗的 ICH 队列中开发的死亡率预测工具。我们旨在比较和评估两种模型在预测接受手术干预的 ICH 患者死亡率方面的外部有效性。对 2018 年 1 月至 2020 年 3 月期间在秘鲁国家医院收治的所有自发性 ICH 患者进行了回顾性研究。我们比较了 ICH 评分的受试者工作特征曲线下面积 (AUC) 和 ICH-GS 的住院、30 天和 6 个月死亡率预测。该研究方案得到了机构审查委员会的批准。共有 73 名患者(中位年龄 62 岁,56.2% 男性)被纳入研究。平均 ICH 和 ICH-GS 评分分别为 2.5 和 8.7,分别。住院、30 天和 6 个月死亡率分别为 37%、27.4% 和 37%。ICH 评分的住院、30 天和 6 个月死亡率的 AUC 分别为 0.69、0.71 和 0.69,ICH-GS 评分分别为 0.64、0.65 和 0.68。在这项研究中,ICH 评分和 ICH-GS 在预测手术治疗患者的住院、30 天和 6 个月死亡率方面具有中等的辨别能力. 其他研究应评估手术干预是否会影响这些预后模型的辨别力,以便根据特定人群制定预测评分

更新日期:2021-07-18
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