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Carbon nanomaterials: synthesis and applications to development of electrochemical sensors in determination of drugs and compounds of clinical interest
Reviews in Analytical Chemistry ( IF 4.3 ) Pub Date : 2020-01-17 , DOI: 10.1515/revac-2019-0017
Laís S. Porto 1 , Daniela N. Silva 1 , Ana Elisa F. de Oliveira 1 , Arnaldo C. Pereira 1 , Keyller B. Borges 1
Affiliation  

Abstract It is notorious that researches related to electrochemical sensors increased significantly due the promising characteristics that these devices present such as the possibility of obtaining information, with minimum manipulation of the studied system, in real time, and with low environmental impact. This article covers the carbon nanomaterials, presenting important aspects such as main properties, synthesis methods, and the application of these materials in the development of electrochemical sensors for the analysis of drugs and compounds of clinical interest. In this context, drug analysis is extremely important for quality control, to ensure that the medicine fulfills its role effectively without possible complications that could compromise the patient’s health and quality of life. In addition, analytical methods capable of determining compounds of clinical interest in biological fluids are extremely important for the indication of effective diagnoses. Thus, the versatility, selectivity, and portability of the electroanalytical techniques make the electrochemical sensors a favorite tool for the determination of drugs and compounds of clinical interest. It will be possible to follow in the present work that carbon nanomaterials have excellent thermal and electrical conductivity, strong adsorption capacity, high electrocatalytic effect, high biocompatibility, and high surface area. The possibility of formation of different composite materials based on carbonaceous nanomaterials that makes these materials promising for the development of analytical sensors, contributing to rapid, sensitive, and low-cost analyses can also be highlighted.

中文翻译:

碳纳米材料:电化学传感器的合成和应用,用于测定临床感兴趣的药物和化合物

摘要 众所周知,与电化学传感器相关的研究显着增加,因为这些设备具有获得信息的可能性,对研究系统的操作最少,实时,对环境影响低。本文涵盖碳纳米材料,介绍了重要方面,例如主要性质、合成方法以及这些材料在开发用于分析临床感兴趣的药物和化合物的电化学传感器中的应用。在这种情况下,药物分析对于质量控制极其重要,以确保药物有效发挥作用,而不会出现可能危及患者健康和生活质量的并发症。此外,能够确定生物体液中具有临床意义的化合物的分析方法对于有效诊断的指示极为重要。因此,电分析技术的多功能性、选择性和便携性使电化学传感器成为测定临床感兴趣的药物和化合物的常用工具。在目前的工作中,碳纳米材料具有优良的导热性和导电性,吸附能力强,电催化效果好,生物相容性好,比表面积大。基于碳质纳米材料形成不同复合材料的可能性,使这些材料有望用于分析传感器的发展,有助于快速、灵敏和低成本的分析。
更新日期:2020-01-17
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