When titanium dioxide (TiO₂) particles are irradiated with ultrasound, the production of reactive oxygen species (ROS) is enhanced. The application of this phenomenon to infection prevention and cancer treatment has been extensively studied. However, to date, it has not been adequately verified whether the use of TiO₂ particles induce the optimal production of ROS. In this study, we compared the enhancement of dihydroxybenzoic acid (DHBA) production as a quantification of ROS production when TiO₂ and other particles were irradiated with ultrasound. The results suggested that the production of DHBA was enhanced with the use of TiO₂ particles as compared with the use of other particles. © 2021 Institute of Electrical Engineers of Japan. Published by Wiley Periodicals LLC.

中文翻译：

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颗粒类型对超声刺激抗感染系统中活性氧产生的影响

当用超声波照射二氧化钛 (TiO ₂ ) 颗粒时，活性氧 (ROS) 的产生会增强。这种现象在感染预防和癌症治疗中的应用已得到广泛研究。然而，迄今为止，尚未充分验证使用 TiO ₂颗粒是否能诱导最佳的 ROS 产生。在这项研究中，我们比较了二羟基苯甲酸 (DHBA) 生成的增强作为 ROS 生成的量化，当 TiO ₂和其他粒子用超声波照射时。结果表明，使用 TiO ₂提高了 DHBA 的产量颗粒与其他颗粒的使用相比。© 2021 日本电气工程师学会。由 Wiley Periodicals LLC 出版。