Since the first Oxford Survey of Childhood Cancer's results were published, people have become more aware of the risks associated with prenatal exposure from diagnostic x rays. As a result, it has since been the subject of many studies. In this review, the results of recent epidemiological studies are summarized. The current international guidelines for diagnostic x-ray examinations were compared to the review. All epidemiological studies starting from 2007 and all relevant international guidelines were included. Apart from one study that involved rhabdomyosarcoma, no statistically significant associations were found between prenatal exposure to x rays and the development of cancer during 2007-2020. Most of the studies were constrained in their design due to too small a cohort or number of cases, minimal x-ray exposure, and/or data obtained from the exposed mothers instead of medical reports. In one of the studies, computed tomography exposure was also included, and this requires more and longer follow-up in successive studies. Most international guidelines are comparable, provide risk coefficients that are quite conservative, and discourage abdominal examinations of pregnant women.

中文翻译：

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产前 X 射线暴露与患儿科癌症的风险 - 风险标记的系统回顾和国际指南的比较。

自从第一次牛津儿童癌症调查结果发表以来，人们越来越意识到产前暴露于诊断性 X 射线的风险。因此，它一直是许多研究的主题。本综述总结了最近的流行病学研究结果。现行国际诊断 X 射线检查指南与综述进行了比较。2007 年以来的所有流行病学研究和所有相关国际指南均包含在内。除了一项涉及横纹肌肉瘤的研究外，没有发现 2007 年至 2020 年期间产前 X 射线暴露与癌症发展之间存在统计学上的显着关联。大多数研究的设计受到限制，原因是队列或病例数量太小、X 射线暴露最少和/或从受暴露母亲那里获得的数据而不是医疗报告。其中一项研究还包括计算机断层扫描暴露，这需要在连续研究中进行更多、更长时间的随访。大多数国际指南具有可比性，提供的风险系数相当保守，并且不鼓励孕妇进行腹部检查。