The Tribolium castaneum (Herbst) (Coleoptera: Tenebrionidae) commonly known as red flour beetle is the most damaging secondary pest of cereal grains because it consumes less and spoils more grains by causing grain heating during storage. The present research is conducted for determination of toxicity of insect growth regulators (IGRs) and Beauveria bassiana (Balsamo) (Vuillemin, Hypocreales: Cordycipitaceae) separately and also in combination against larvae of T. castaneum. Completely randomized design (CRD) was used with three repetitions of all treatments. Mortality was noted after 5, 7 and 10 days of exposure to treatments. Regarding the alone application of IGRs i.e. pyriproxyfen, lufenuron and buprofezin highest larval mortality was up to 68.63%, 64.33% and 56.26% respectively, significant at their highest applied concentration of 0.15% after exposure period of 10 days. In the case of B. bassiana highest mortality of 59.25% was observed at 1.5 × 10⁸ conidia per gram after 10 days of exposure. Results of the present study revealed that combined application of IGRs and B. bassiana significantly increased the larval mortality of T. castaneum and highest mortality (83.04%) was recorded with the application of pyriproxyfen along with B. bassiana after 10 days post exposure on wheat grains. The current findings suggested that combinations of B. bassiana with IGRs have a synergistic response against Tribolium castaneum as it resulted in higher mortality rather than the solitary applications and it may also discourage the resistance development in insect pests against these insecticides.

在赤拟谷盗（秋天）（鞘翅目：拟步甲科）俗称赤拟谷盗是谷粒最损坏次要害虫，因为它消耗更少的和通过存储过程中引起晶粒加热赃物更多的晶粒。本研究旨在分别测定昆虫生长调节剂 (IGR) 和白僵菌(Balsamo) (Vuillemin, Hypocreales: Cordycipitaceae) 对T. castaneum幼虫的毒性. 使用完全随机设计 (CRD)，所有处理重复 3 次。在接触治疗 5、7 和 10 天后记录死亡率。关于单独应用 IGR，即吡丙醚、虱螨脲和丁苯丙嗪的最高幼虫死亡率分别高达 68.63%、64.33% 和 56.26%，在暴露 10 天后的最高应用浓度为 0.15% 时显着。在B. bassiana的情况下，在暴露 10 天后，每克1.5 × 10 ⁸分生孢子的最高死亡率为 59.25% 。本研究的结果表明，IGRs 和B. bassiana 的联合应用显着增加了T. castaneum的幼虫死亡率在小麦籽粒暴露后 10 天后，将吡丙醚与B. bassiana一起应用记录到最高死亡率 (83.04%) 。目前的研究结果表明，B. bassiana与 IGR 的组合对Tribolium castaneum具有协同反应，因为它导致更高的死亡率而不是单独应用，并且它还可能阻碍害虫对这些杀虫剂的抗性发展。