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Total synthesis of Neocosmosin A
Synthetic Communications ( IF 2.1 ) Pub Date : 2021-07-15 , DOI: 10.1080/00397911.2021.1952435
Manmohan Reddy Depa 1, 2 , Suneetha Potla 1, 2 , Umesh C. Narkhede 1 , Vinod D. Jadhav 1 , Gattu Sridhar 3 , Siddaiah Vidavalur 2
Affiliation  

Abstract

An alternative synthetic route to (−)-Neocosmosin A has been synthesized from commercially available (R)-propylene oxide and 4-Methoxysalicylic acid as starting materials. The key steps involved in the synthesis are alkylation of 1,3-dithiane and Yamaguchi macrolactonization.



中文翻译:

Neocosmosin A的全合成

摘要

(-)-Neocosmosin A 的替代合成路线已由市售的 ( R )-环氧丙烷和 4-甲氧基水杨酸作为起始材料合成。合成中涉及的关键步骤是 1,3-二噻烷的烷基化和 Yamaguchi 大环内酯化。

更新日期:2021-08-25
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