Purpose of Review

It was reported that migraine was associated with increased vascular risks, and the association between high blood pressure (BP) and migraine was believed by some to be the missing link. The current review focused on the associations between migraine and hypertension and BP per se, and evidence on the directionality of the associations was also reviewed.

Recent Findings

In cross-sectional studies, the findings regarding whether migraine was associated with hypertension were inconsistent, and positive, neutral, or even inverse associations were reported. When individual BP parameters were examined separately, migraine was associated with higher diastolic BPs, and perhaps lower pulse pressures, although the associations with systolic BPs were incongruent. When studies mainly recruiting elderly patients are excluded, it appeared that studies reporting a positive association between migraine and high BPs, particularly high diastolic BPs, outnumbered those with an inverse or neutral association. In longitudinal studies, there was evidence that migraine patients were at increased risks of developing hypertension at follow-up. However, studies examining whether high BP could predict new-onset migraine yielded conflicting results.

Summary

The association between migraine and hypertension is still a controversial issue, and a firm conclusion is precluded by the heterogeneities in methodologies and study populations. Migraine patients are at increased risk of developing hypertension. However, whether hypertension predicts migraine remains inconclusive. Further studies are needed to clarify the complicated association between BP and migraine.

中文翻译：

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高血压和偏头痛：是时候重新审视证据了

审查目的

据报道，偏头痛与血管风险增加有关，一些人认为高血压 (BP) 和偏头痛之间的关联是缺失的环节。目前的审查侧重于偏头痛和高血压与血压本身之间的关联，并且还审查了有关关联方向性的证据。

最近的发现

在横断面研究中，关于偏头痛是否与高血压相关的研究结果并不一致，报告了正相关、中性甚至负相关。当单独检查单个 BP 参数时，偏头痛与较高的舒张压相关，并且可能与较低的脉压相关，尽管与收缩压的相关性不一致。当主要招募老年患者的研究被排除在外时，似乎报告偏头痛与高血压（尤其是高舒张压）之间呈正相关的研究数量超过了呈负相关或中性关联的研究。在纵向研究中，有证据表明偏头痛患者在随访中患高血压的风险增加。然而，

概括

偏头痛和高血压之间的关联仍然是一个有争议的问题，由于方法学和研究人群的异质性，无法得出明确的结论。偏头痛患者患高血压的风险增加。然而，高血压是否预示偏头痛仍无定论。需要进一步的研究来阐明 BP 与偏头痛之间的复杂关联。