Purpose of Review

This article reviews the acquisition protocols and image interpretation for ¹⁸F-fluorodeoxyglucose (¹⁸F-FDG) imaging with positron emission tomography (PET) applied to the evaluation of myocardial viability and inflammation.

Recent Findings

Cardiac PET with ¹⁸F-FDG provides essential information for the assessment of myocardial viability and inflammation and is usually combined with PET perfusion imaging using ⁸²Rb or ¹³N-ammonia. Viable myocardium maintains glucose metabolism which can be detected via the uptake of ¹⁸F-FDG by PET imaging. The patient is prepared for viability imaging by shifting the metabolism of the heart to maximize the uptake of glucose and hence of ¹⁸F-FDG. Comparison of the ¹⁸F-FDG and myocardial perfusion images allows distinction between regions of the myocardium that are hibernating and thus may recover function with intervention, from those that are infarcted. Increased glucose utilization in the inflammatory cells also makes ¹⁸F-FDG a useful imaging technique in conditions such as cardiac sarcoidosis. Here, suppression of normal myocardial uptake is essential for accurate image interpretation.

Summary

¹⁸F-FDG PET broadens the scope of information potentially available through a cardiac PET study. With careful patient preparation, it provides valuable insights into myocardial viability and inflammatory processes such as sarcoidosis.

中文翻译：

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PET 18F-FDG 活力和炎症研究的采集、处理和解释

审查目的

本文回顾了¹⁸ F-氟脱氧葡萄糖 ( ¹⁸ F-FDG) 成像的采集协议和图像解释，正电子发射断层扫描 (PET) 应用于评估心肌活力和炎症。

最近的发现

含有¹⁸ F-FDG 的心脏 PET为评估心肌活力和炎症提供了重要信息，通常与使用⁸² Rb 或¹³ N-氨的PET 灌注成像相结合。存活心肌维持葡萄糖代谢，可通过¹⁸ F-FDG的摄取通过 PET 成像进行检测。通过改变心脏的代谢以最大化葡萄糖的摄取，从而使¹⁸ F-FDG的摄取最大化，患者为生存能力成像做好了准备。^{18 的}比较F-FDG 和心肌灌注图像允许区分处于冬眠状态的心肌区域，因此可以通过干预恢复功能，从那些梗死的区域。炎症细胞中葡萄糖利用的增加也使¹⁸ F-FDG 成为一种有用的成像技术，例如心脏结节病。在这里，抑制正常的心肌摄取对于准确的图像解释至关重要。

总结

¹⁸ F-FDG PET 拓宽了可通过心脏 PET 研究获得的信息范围。通过仔细的患者准备，它提供了对心肌活力和炎症过程（如结节病）的宝贵见解。