Introduction: Due to the coronavirus disease 19 (COVID-19) pandemic, multiple measures have been implemented including social distancing and curfews. Both the disease and measures might cause stress, particularly in persons at risk, such as liver transplant (LT) recipients. Here, we evaluated the impact on psychosocial well-being of LT recipients. Methods: Seventy-nine LT recipients and 83 nontransplanted controls participated in this study. Questionnaires comprising the WHO-five well-being index (WHO-5), the University of California at Los Angeles (UCLA) Loneliness Scale, and the preliminary COVID-19 Pandemic Mental Health Questionnaire (CoPaQ) were distributed among them. For the WHO-5 and UCLA Loneliness Scale, means of sum scores were compared between both groups, while a comparison on item level was conducted for the CoPaQ. Results: The general well-being was similar in LT recipients and controls (WHO-5: 64.0 ± 20.5% vs. 66.4 ± 17.3%), while the UCLA Loneliness Scale indicated a higher level of perceived social isolation (1.90 ± 0.51 vs. 1.65 ± 0.53, p = 0.001). The CoPaQ indicated higher risk perception regarding health issues, in particular concerning the fear of having severe consequences in case of a COVID-19 infection (3.1 ± 1.1 vs. 2.2 ± 1.3, p #x3c; 0.001), higher risk-avoiding behavior and stronger adherence to pandemic measures in LT recipients. Conclusion: During the COVID-19 pandemic, LT recipients displayed a higher risk perception, a more pronounced risk-avoiding behavior and a higher perception of loneliness, while the overall well-being was comparable to nontransplanted controls.
Visc Med

中文翻译：

---

COVID-19 大流行期间肝移植受者的社会心理负担

简介：由于冠状病毒病 19 (COVID-19) 大流行，已实施多项措施，包括保持社交距离和宵禁。疾病和措施都可能导致压力，特别是在有风险的人中，例如肝移植 (LT) 接受者。在这里，我们评估了对 LT 接受者的社会心理健康的影响。方法：79 名 LT 受者和 83 名非移植对照参与了这项研究。问卷包括 WHO-5 幸福指数 (WHO-5)、加州大学洛杉矶分校 (UCLA) 孤独量表和初步的 COVID-19 大流行心理健康问卷 (CoPaQ)。对于 WHO-5 和 UCLA 孤独感量表，比较了两组之间的总分平均值，同时对 CoPaQ 进行了项目级别的比较。结果： LT 接受者和对照组的总体幸福感相似（WHO-5：64.0 ± 20.5% 对 66.4 ± 17.3%），而 UCLA 孤独量表表明感知到的社会孤立程度更高（1.90 ± 0.51 vs. 1.65 ± 0.53, p= 0.001)。CoPaQ 表明对健康问题有更高的风险认知，特别是担心在 COVID-19 感染的情况下会产生严重后果（3.1 ± 1.1 对 2.2 ± 1.3，p #x3c；0.001）、更高的风险规避行为和LT 接受者更严格地遵守流行病措施。结论：在 COVID-19 大流行期间，LT 接受者表现出更高的风险感知、更明显的风险规避行为和更高的孤独感，而整体幸福感与非移植对照组相当。
粘性医学