A previously immune-naive world population is experiencing natural infection with SARS-CoV-2. Severe COVID-19 predominantly impacts adults, yet multisystem inflammatory disorder primarily impacts children. Herein, we discuss known clinical and biological features of SARS-CoV-2 in children and reflect on currently identified immune features and discuss what remains unknown.

中文翻译：

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儿童和 SARS-CoV-2

以前免疫天真的世界人口正在经历 SARS-CoV-2 的自然感染。严重的 COVID-19 主要影响成年人，但多系统炎症性疾病主要影响儿童。在此，我们讨论了儿童 SARS-CoV-2 的已知临床和生物学特征，并反思目前确定的免疫特征并讨论尚不清楚的内容。