Only an estimated 62% of Indian children under the age of 2 years are fully immunized. We examined the association between India's Mission Indradhanush (MI)—a periodic intensification of the routine immunization program—which was implemented in phases across districts between March 2015 and July 2017, and routine vaccination coverage and timeliness among children. We used data from a 2015 to 2016 national survey of children (n = 29,532) and employed difference-in-difference regressions to examine binary indicators of receipt of 11 vaccines and whether vaccines were received at recommended ages. The full immunization rate was 27% higher among children under 2 years old residing in MI phase 1 and 2 districts (intervention group) as compared with those residing elsewhere (control group). The rate of receiving all vaccines at recommended ages was 8% higher in the intervention group. Receiving doses of oral polio vaccine (OPV) birth dose, OPV dose 1 (OPV1), OPV2, OPV3, bacillus Calmette–Guérin, and hepatitis B birth dose vaccines were 9%, 9%, 11%, 16%, 5%, and 19% higher in the intervention group than the control group, respectively. More research is required on the cost-effectiveness of investing in MI-type programs as compared with routine immunization.

中文翻译：

---

通过定期加强常规免疫提高疫苗接种覆盖率和及时性：来自因德拉达努什任务的证据

据估计，只有 62% 的 2 岁以下印度儿童完全接种了疫苗。我们研究了印度的 Mission Indradhanush (MI)——定期强化常规免疫计划——于 2015 年 3 月至 2017 年 7 月期间在各地区分阶段实施，与儿童的常规疫苗接种覆盖率和及时性之间的关联。我们使用了 2015 年至 2016 年全国儿童调查的数据（n = 29,532) 并采用差异回归来检查接受 11 种疫苗的二元指标以及是否在建议的年龄接受了疫苗。与居住在其他地方的儿童（对照组）相比，居住在 MI 1 期和 2 区（干预组）的 2 岁以下儿童的完全免疫率高出 27%。干预组在推荐年龄接受所有疫苗的比率高出 8%。口服脊髓灰质炎疫苗 (OPV) 出生剂量、OPV 剂量 1 (OPV1)、OPV2、OPV3、卡介苗和乙型肝炎出生剂量疫苗的接种剂量分别为 9%、9%、11%、16%、5%，干预组比对照组分别高出 19% 和 19%。与常规免疫相比，需要对 MI 型项目进行投资的成本效益进行更多研究。