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A Conformable, Gas-Permeable, and Transparent Skin-Like Micromesh Architecture for Glucose Monitoring
Advanced Healthcare Materials ( IF 10.0 ) Pub Date : 2021-07-14 , DOI: 10.1002/adhm.202100046
Ya-Lei Li 1 , Yan-Hua Liu 1 , Lin-Sen Chen 1 , Jian-Long Xu 2
Affiliation  

Monitoring the concentration of useful biomarkers via electronic skins (e-skins) is highly important for the development of wearable health management systems. While some biosensor e-skins with high flexibility, sensitivity, and stability have been developed, little attention has been paid to their long-term comfortability and optical transparency. Here, a conformable, gas permeable, and transparent skin-like Cu2O@Ni micromesh structural glucose monitoring patch is reported. With its self-supporting micromesh structure, the skin-like glucose monitoring patch exhibits excellent shape conformability, high gas permeability, and high optical transmittance. The skin-like glucose biosensor achieves real-time monitoring of glucose concentrations with high sensitivity (15 420 µA cm2mM1), low detection limit (50 nM), fast response time (<2 s), high selectivity, and long-term stability. These desirable performance properties arise from the synergistic effects of the self-supporting micromesh configuration, high conductivity of the metallic Ni micromesh, and high electrocatalytic activities of the Cu2O toward glucose. This work presents a versatile and efficient strategy for constructing conformable, gas permeable, and transparent biosensor e-skins with excellent practicability towards wearable electronics.

中文翻译:

一种用于血糖监测的舒适、透气且透明的类皮肤微网结构

通过电子皮肤(e-skins)监测有用生物标志物的浓度对于可穿戴健康管理系统的开发非常重要。虽然已经开发了一些具有高灵活性、灵敏度和稳定性的生物传感器电子皮肤,但很少有人关注它们的长期舒适性和光学透明度。在这里,报道了一种舒适的、透气的、透明的皮肤状 Cu 2 O@Ni 微网结构葡萄糖监测贴片。凭借其自支撑微网结构,皮肤状葡萄糖监测贴片具有优异的形状一致性、高透气性和高透光率。皮肤状葡萄糖生物传感器以高灵敏度(15 420 µA cm 2mM 1 )、低检测限(50 nM)、快速响应时间(<2 s)、高选择性和长期稳定性。这些理想的性能特性源于自支撑微网结构、金属 Ni 微网的高电导率和 Cu 2 O 对葡萄糖的高电催化活性的协同效应。这项工作提出了一种通用且有效的策略,用于构建对可穿戴电子产品具有出色实用性的贴合、透气和透明的生物传感器电子皮肤。
更新日期:2021-09-22
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