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Associations between physical activity, sedentary behaviour and left ventricular structure and function from the Echocardiographic Study of Latinos (ECHO-SOL)
Open Heart Pub Date : 2021-07-01 , DOI: 10.1136/openhrt-2021-001647
Andrew E Berdy 1 , Bharathi Upadhya 2 , Sonia Ponce 3 , Katrina Swett 4 , Richard B Stacey 1 , Robert Kaplan 4 , Priscilla M Vasquez 3 , Qibin Qi 4 , Neil Schneiderman 5 , Barry E Hurwitz 5 , Martha L Daviglus 6 , Mayank Kansal 6 , Kelly R Evenson 7 , Carlos J Rodriguez 4
Affiliation  

Objective The cross-sectional association between accelerometer-measured physical activity (PA), sedentary behaviour (SB) and cardiac structure and function is less well described. This study’s primary aim was to compare echocardiographic measures of cardiac structure and function with accelerometer measured PA and SB. Methods Participants included 1206 self-identified Hispanic/Latino men and women, age 45–74 years, from the Echocardiographic Study of Latinos. Standard echocardiographic measures included M-mode, two-dimensional, spectral, tissue Doppler and myocardial strain. Participants wore an Actical accelerometer at the hip for 1 week. Results The mean±SE age for the cohort was 56±0.4 years, 57% were women. Average moderate to vigorous PA (MVPA) was 21±1.1 min/day, light PA was 217±4.2 min/day and SB was 737±8.1 min/day. Both higher levels of light PA and MVPA (min/day) were associated with lower left ventricular (LV) mass index (LVMI)/end-diastolic volume and a lower E/e′ ratio. Higher levels of MVPA (min/day) were associated with better right ventricular systolic function. Higher levels of SB were associated with increased LVMI. In a multivariable linear regression model adjusted for demographics and cardiovascular disease modifiable factors, every 10 additional min/day of light PA was associated with a 0.03 mL/m2 increase in left atrial volume index (LAVI) (p<0.01) and a 0.004 cm increase in tricuspid annular plane systolic excursion (p<0.01); every 10 additional min/day of MVPA was associated with a 0.18 mL/m2 increase in LAVI (p<0.01) and a 0.24% improvement in global circumferential strain (p<0.01). Conclusions Our findings highlight the potential positive association between the MVPA and light PA on cardiac structure and function. Data may be obtained from a third party and are not publicly available. All HCHS-SOL data will be included in a limited access database that will be available to the larger scientific public as part of the main HCHS-SOL study database for public use. It will be encouraged that all use of data and publications from ancillary studies invite the participation of the ancillary study PI and coinvestigators.

中文翻译:

来自拉丁裔超声心动图研究 (ECHO-SOL) 的身体活动、久坐行为与左心室结构和功能之间的关联

目的 加速度计测量的身体活动 (PA)、久坐行为 (SB) 与心脏结构和功能之间的横断面关联鲜有描述。本研究的主要目的是比较心脏结构和功能的超声心动图测量值与加速度计测量的 PA 和 SB。方法 参与者包括来自拉丁裔超声心动图研究的 1206 名自我认定的西班牙裔/拉丁裔男性和女性,年龄在 45-74 岁之间。标准的超声心动图测量包括 M 型、二维、频谱、组织多普勒和心肌应变。参与者在臀部佩戴了一个 Actical 加速度计 1 周。结果队列的平均±SE年龄为56±0.4岁,57%为女性。平均中度至剧烈 PA (MVPA) 为 21±1.1 分钟/天,轻度 PA 为 217±4.2 分钟/天,SB 为 737±8.1 分钟/天。较高水平的光 PA 和 MVPA(分钟/天)与较低的左心室 (LV) 质量指数 (LVMI)/舒张末期容积和较低的 E/e' 比值相关。更高水平的 MVPA(分钟/天)与更好的右心室收缩功能相关。较高水平的 SB 与增加的 LVMI 相关。在针对人口统计学和心血管疾病可改变因素调整的多变量线性回归模型中,每增加 10 分钟/天的轻度 PA 与左心房容积指数 (LAVI) (p<0.01) 增加 0.03 mL/m2 和 0.004 cm三尖瓣环平面收缩期偏移增加(p<0.01);MVPA 每增加 10 分钟/天,LAVI 增加 0.18 mL/m2(p<0.01),整体周向应变增加 0.24%(p<0.01)。结论 我们的研究结果强调了 MVPA 和轻 PA 之间对心脏结构和功能的潜在正相关关系。数据可能从第三方获得并且不公开可用。所有 HCHS-SOL 数据都将包含在一个有限访问数据库中,该数据库将作为主要 HCHS-SOL 研究数据库的一部分提供给更多的科学公众,供公众使用。鼓励所有辅助研究数据和出版物的使用邀请辅助研究 PI 和共同研究者参与。所有 HCHS-SOL 数据都将包含在一个有限访问数据库中,该数据库将作为主要 HCHS-SOL 研究数据库的一部分提供给更多的科学公众,供公众使用。鼓励所有辅助研究数据和出版物的使用邀请辅助研究 PI 和共同研究者参与。所有 HCHS-SOL 数据都将包含在一个有限访问数据库中,该数据库将作为主要 HCHS-SOL 研究数据库的一部分提供给更多的科学公众,供公众使用。鼓励所有辅助研究数据和出版物的使用邀请辅助研究 PI 和共同研究者参与。
更新日期:2021-07-14
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