In this work, a borosilicate glass sample (5SiO₂–45B₂O₃–20Na₂O–25CaO–5Ag₂O) was added to nano-sized carbonated hydroxyapatite (CHA) powders with different contents up to 20 wt% to improve the bioactivity, antibacterial effect, physical and mechanical properties of the resulting nanocomposites. The CHA and BG nanocomposite powders were mixed, milled with a high-energy ball mill, then pressed into pellets under hydraulic pressure, and finally sintered in muffle at 650 ºC. Subsequently, the sintered samples were subjected to X-ray diffraction (XRD) technique, Fourier transform infrared (FTIR) spectroscopy and scanning electron microscopy (SEM) to examine their structure, chemical composition and microstructure, respectively. Furthermore, the physical and mechanical properties of the sintered nanocomposites were also measured. Moreover, the in vitro bioactivity of the prepared nanocomposites was tested after being soaked in a simulated body fluid (SBF) solution for 10 days and their surfaces were then examined with XRD and SEM. In addition, the antibacterial behavior of these samples was tested against E. coli and S. aureus by the disc-diffusion method. The results obtained indicated that the sample with the highest BG content possessed the best bioactivity, antibacterial effect, physical and mechanical properties. Based on these results, the prepared nanocomposites can be used in various biomedical applications.

在这项工作中，硼硅酸盐玻璃样品 (5SiO ₂ –45B ₂ O ₃ –20Na ₂ O–25CaO–5Ag ₂O) 被添加到不同含量的纳米碳酸羟基磷灰石 (CHA) 粉末中，最高可达 20 wt%，以提高所得纳米复合材料的生物活性、抗菌效果、物理和机械性能。将 CHA 和 BG 纳米复合粉末混合，用高能球磨机研磨，然后在液压下压成颗粒，最后在 650 ºC 下在马弗炉中烧结。随后，对烧结样品进行 X 射线衍射 (XRD) 技术、傅里叶变换红外 (FTIR) 光谱和扫描电子显微镜 (SEM)，分别检查其结构、化学成分和微观结构。此外，还测量了烧结纳米复合材料的物理和机械性能。而且，在模拟体液 (SBF) 溶液中浸泡 10 天后，测试制备的纳米复合材料的体外生物活性，然后用 XRD 和 SEM 检查其表面。此外，还对这些样品的抗菌行为进行了测试大肠杆菌和金黄色葡萄球菌通过圆盘扩散法。结果表明，BG含量最高的样品具有最好的生物活性、抗菌效果、物理和机械性能。基于这些结果，制备的纳米复合材料可用于各种生物医学应用。