A one-pot four component condensation of isatin, sarcosine, 2-[2-oxo-1-(prop-2-ynyl)indolin-3-ylidene]malononitrile and aryl azides has been reported for the synthesis of novel dispirooxindole pyrrolidine linked 1,2,3-triazole conjugates using Cu(I) as a catalyst in PEG-400 by stereoselective [3 + 2] azide-alkyne cycloaddition followed by [3 + 2] azomethine ylide and alkene cycloaddition. Structures have been confirmed by spectral and X-ray studies. Crystal packing of 5a has also been reported. Rapid reaction, easy work-up and high yields are the salient features of the present protocol.

中文翻译：

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在 PEG-400 中合成新型二螺环吲哚吡咯烷连接的 1,2,3-三唑异立体立体和区域选择性 [3 + 2] 环加成反应的一锅四组分缩合反应

据报道，靛红、肌氨酸、2-[2-oxo-1-(prop-2-ynyl)indolin-3-ylidene]丙二腈和芳基叠氮化物的一锅四组分缩合反应可用于合成新型二螺环吲哚吡咯烷连接 1 ,2,3-三唑缀合物使用 Cu(I) 作为 PEG-400 中的催化剂，通过立体选择性 [3 + 2] 叠氮化物 - 炔烃环加成，然后是 [3 + 2] 偶氮甲碱叶立德和烯烃环加成。结构已通过光谱和 X 射线研究得到证实。5a 的晶体堆积也有报道。快速反应、易于处理和高产率是本协议的显着特点。