As a novel extension, the Kabachnik–Fields reaction was applied to the synthesis of alkyl α-aminomethyl-phenylphosphinates, and the double phospha-Mannich reaction was utilized in the preparation of bis(alkoxyphenylphosphinylmethyl)amines. A total of 27 new aminophosphinate derivatives were synthesized by the microwave-assisted solvent-free condensation of alkyl phenyl-H-phosphinates, paraformaldehyde, and primary or secondary amines. The starting P-species were also prepared under microwave conditions. The formation of the N-methylated aminomethyl-phenylphosphinate by-products was also investigated.

中文翻译：

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微波辅助 Kabachnik-Fields 反应合成 α-氨基甲基-苯基次膦酸烷基酯和 N,N-双（烷氧基苯基膦基甲基）胺

作为一个新的扩展，Kabachnik-Fields 反应被应用于合成烷基 α-氨基甲基-苯基次膦酸酯，双磷酸-Mannich 反应被用于制备双（烷氧基苯基膦基甲基）胺。通过烷基苯基-H-次膦酸盐、多聚甲醛和伯胺或仲胺的微波辅助无溶剂缩合，共合成了 27 种新的氨基次膦酸盐衍生物。起始 P 物种也在微波条件下制备。还研究了 N-甲基化氨基甲基-苯基次膦酸盐副产物的形成。