ABSTRACT

Introduction: Acceptance of COVID-19 vaccines is critical to personal health, protecting vulnerable populations, reopening socio-economic life, and achieving population health and safety through immunity. The primary aim of this review was to investigate the extent and determinants of COVID-19 vaccine hesitancy in South Africa to inform the development of strategies to address it. A secondary aim was to enhance understandings of and responses to vaccine hesitancy more generally in South Africa, with potential positive effect on vaccination uptake during and beyond the COVID-19 pandemic.

Areas covered: We reviewed the findings from surveys conducted in South Africa from February 2020 to March 2021 that investigated acceptance of COVID-19 vaccines. Surveys were identified through searching electronic databases of peer-reviewed and gray literature and contacting experts.

Expert opinion: The review reveals the inherently social nature of COVID-19 vaccine hesitancy in South Africa, potentially influenced by age, race, education, politics, geographical location, and employment. Along with the provision of information, COVID-19 vaccine communication strategies need to form part of broader trust-building measures that focus on relationships, transparency, participation, and justice. The pandemic also provides a unique opportunity to positively intervene and reduce vaccine hesitancy trends more generally in South Africa and potentially elsewhere.

摘要

简介：接受 COVID-19 疫苗对个人健康、保护弱势群体、重新开放社会经济生活以及通过免疫实现人口健康和安全至关重要。本综述的主要目的是调查南非对 COVID-19 疫苗犹豫不决的程度和决定因素，为制定解决该问题的策略提供信息。第二个目标是在南非更普遍地加强对疫苗犹豫的理解和应对，这对 COVID-19 大流行期间和之后的疫苗接种产生潜在的积极影响。

涵盖的领域：我们回顾了 2020 年 2 月至 2021 年 3 月在南非进行的调查结果，这些调查调查了 COVID-19 疫苗的接受情况。通过搜索同行评审和灰色文献的电子数据库并联系专家来确定调查。

专家意见：审查揭示了南非对 COVID-19 疫苗犹豫不决的内在社会性质，可能受年龄、种族、教育、政治、地理位置和就业的影响。除了提供信息外，COVID-19 疫苗传播策略还需要成为更广泛的信任建立措施的一部分，这些措施侧重于关系、透明度、参与和正义。大流行还提供了一个独特的机会，可以在南非和其他地方更普遍地积极干预和减少疫苗犹豫趋势。