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Full-field optical coherence tomography using tunable-path-difference source for three-dimensional multi-layered imaging with enhanced signal-to-noise ratio
Optics and Lasers in Engineering ( IF 4.6 ) Pub Date : 2021-07-12 , DOI: 10.1016/j.optlaseng.2021.106727
Jaeheung Kim 1 , Sang Min Park 1 , Gyeong Hun Kim 1 , Minyoung Park 2 , Jeesu Kim 1 , Chang-Seok Kim 1
Affiliation  

We demonstrate a novel scheme for a full-field optical coherence tomography (FF-OCT) system using a tunable-path-difference source (TPDS). Recently, the comb-spacing-swept source (CSWS) method, including TPDS, has been successfully applied to improve the stability of three-dimensional (3D) time-domain (TD)-FF-OCT imaging by eliminating the mechanical scanning of the reference path, which has been the main source of undesirable noise in general TD-OCT. However, CSWS-OCT has the drawback of a degraded signal-to-noise ratio (SNR) from a duplicated interferometer structure. In this study, we improve the configuration of the TPDS so that it can be connected directly to the measurement interferometer, including the sample and reference paths of the OCT system. In our novel TPDS-OCT, a propagating optical path through only a single interferometer was critically helpful in enhancing the SNR while retaining the benefits of CSWS-OCT, and a free-space full-field interferometer of dual-input Mach–Zehnder type also has an even higher imaging performance owing to the simultaneous exposure of optical intensity into the camera and the short image acquisition time laterally. We theoretically and experimentally demonstrated the benefits of TPDS-OCT compared with CSWS-OCT in terms of SNR. We also demonstrated 3D multi-layered imaging, which CSWS-OCT cannot achieve owing to its limited SNR.



中文翻译:

使用可调谐路径差源进行具有增强信噪比的三维多层成像的全场光学相干断层扫描

我们展示了一种使用可调路径差源 (TPDS) 的全场光学相干断层扫描 (FF-OCT) 系统的新方案。最近,包括 TPDS 在内的梳间距扫频源 (CSWS) 方法已成功应用于提高三维 (3D) 时域 (TD)-FF-OCT 成像的稳定性,通过消除机械扫描来提高三维 (3D) 时域 (TD)-FF-OCT 成像的稳定性。参考路径,这是一般 TD-OCT 中不良噪声的主要来源。然而,CSWS-OCT 具有重复干涉仪结构导致信噪比 (SNR) 下降的缺点。在这项研究中,我们改进了 TPDS 的配置,使其可以直接连接到测量干涉仪,包括 OCT 系统的样本和参考路径。在我们新颖的 TPDS-OCT 中,仅通过单个干涉仪的传播光路在保留 CSWS-OCT 优点的同时提高 SNR 至关重要,双输入 Mach-Zehnder 类型的自由空间全场干涉仪也具有更高的成像性能光强度同时曝光到相机和横向较短的图像采集时间。我们从理论上和实验上证明了 TPDS-OCT 与 CSWS-OCT 相比在 SNR 方面的优势。我们还展示了 3D 多层成像,由于其有限的 SNR,CSWS-OCT 无法实现。双输入Mach-Zehnder型自由空间全场干涉仪由于光强同时曝光到相机中并且横向图像采集时间短,因此具有更高的成像性能。我们从理论上和实验上证明了 TPDS-OCT 与 CSWS-OCT 相比在 SNR 方面的优势。我们还展示了 3D 多层成像,由于其有限的 SNR,CSWS-OCT 无法实现。双输入Mach-Zehnder型自由空间全场干涉仪由于光强同时曝光到相机中并且横向图像采集时间短,因此具有更高的成像性能。我们从理论上和实验上证明了 TPDS-OCT 与 CSWS-OCT 相比在 SNR 方面的优势。我们还展示了 3D 多层成像,由于其有限的 SNR,CSWS-OCT 无法实现。

更新日期:2021-07-12
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