Our study aimed to evaluate the sensitivity of the sonication tool for the microbiological diagnosis of cardiovascular implantable electronic device infections (CIEDIs). The extracted cardiac implants of 52 patients were assessed: 19 with CIEDI and 33 with elective generator replacement or revision without clinical infection. Sonication fluid culture of explanted CIEDs yielded higher numbers of microorganisms than pocket tissue or swab cultures. The sensitivity of sonication fluid culture was significantly higher than that of pocket swab and tissue culture for microbiological diagnosis of CIEDI. The microorganisms isolated most frequently via sonication of explanted CIEDs were Gram-positive cocci (70%), of which 50% was coagulase-negative Staphylococcus. Sonication fluid culture detected colonization in 36.4% of the non-infected patients. Sonication fluid culture represents a promising diagnostic strategy with increased sensitivity compared to conventional culture methods for microbiological diagnosis of cardiac devices associated with infection and colonization.

我们的研究旨在评估超声工具对心血管植入式电子设备感染 (CIEDI) 的微生物诊断的敏感性。对 52 名患者提取的心脏植入物进行了评估：19 名使用 CIEDI，33 名使用无临床感染的选择性发电机更换或修复。外植 CIED 的超声液体培养产生的微生物数量高于口袋组织或拭子培养物。超声液体培养对CIEDI微生物诊断的敏感性显着高于口袋拭子和组织培养。通过外植 CIED 超声分离最常分离的微生物为革兰氏阳性球菌 (70%)，其中 50% 为凝固酶阴性葡萄球菌. 超声液体培养在 36.4% 的未感染患者中检测到定植。超声液体培养代表了一种很有前途的诊断策略，与用于与感染和定植相关的心脏装置的微生物诊断的传统培养方法相比，具有更高的灵敏度。