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Primary Pleural Squamous Cell Carcinoma, Highly Positive PD-L1, Shows Marked Response to Camrelizumab: A Case Report
Clinical Medicine Insights: Oncology ( IF 1.795 ) Pub Date : 2021-07-12 , DOI: 10.1177/11795549211028571
Yao Wang 1 , Ying Gao 1 , Hai-Ruo Chen 1 , Hong Liu 1 , Xi Fu 1 , Ran Yan 1 , Feng-Ming You 1 , Zhuo-Hong Li 1
Affiliation  

Here, we reported the rare case of primary pleural squamous cell carcinoma (PPSCC) in a 71-year-old male patient. After chemo and targeted therapies, the patient showed continuous tumor progression and clinical deterioration. Fortunately, the patient had a high expression level of PD-L1 (80%) in the tumor tissues. Ultimately, the patient survived for additional 6 months with camrelizumab treatment. In summary, camrelizumab may be a good candidate for the treatment of PPSCC, especially in tumors with high PD-L1 expression.



中文翻译:

原发性胸膜鳞状细胞癌,高阳性 PD-L1,对 Camrelizumab 显示显着反应:病例报告

在这里,我们报告了一名 71 岁男性患者的罕见原发性胸膜鳞状细胞癌 (PPSCC)。在化疗和靶向治疗后,患者表现出持续的肿瘤进展和临床恶化。幸运的是,患者的肿瘤组织中PD-L1的表达水平很高(80%)。最终,患者在接受卡瑞珠单抗治疗后又存活了 6 个月。综上所述,camrelizumab 可能是治疗 PPSCC 的良好候选药物,尤其是在 PD-L1 高表达的肿瘤中。

更新日期:2021-07-12
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