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A New and Effective One-Pot Synthesis of Polysubstituted Carbazoles Starting from β-Nitro-β,γ-Unsaturated-Ketones and Indoles
Asian Journal of Organic Chemistry ( IF 2.7 ) Pub Date : 2021-07-12 , DOI: 10.1002/ajoc.202100342
Alessandro Palmieri 1 , Gabriele Lupidi 2 , Benedetta Bassetti 2 , Roberto Ballini 2 , Marino Petrini 2
Affiliation  

Polyfunctionalized carbazole derivatives have been synthesized by a one-pot reaction between indoles and keto-functionalized nitroolefins. The first reaction step is based on Friedel-Crafts reaction followed by acid-promoted and microwave-assisted intramolecular cyclization.
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中文翻译:

以 β-硝基-β,γ-不饱和酮和吲哚为原料的多取代咔唑的新型高效一锅法合成

多官能化咔唑衍生物已通过吲哚和酮官能化硝基烯烃之间的一锅反应合成。第一个反应步骤基于 Friedel-Crafts 反应,然后是酸促进和微波辅助的分子内环化。
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更新日期:2021-09-13
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