Cancer is the most frequent life-threatening disease which has the highest mortality rate throughout the world. Diagnosis of cancer at the early stage can plays a critical role for its effective and successful treatment. Traditional diagnostic methods for cancer screening are costly, time-consuming, and not practical for repeated screenings. However, a biomarker-based cancer diagnosis is emerging as one of the most promising strategies for early diagnosis, monitoring disease progression, and subsequent cancer treatment. This review describes the recent advances and improvements in the electrochemical biosensors designed for detecting various cancer biomarkers using different signal transduction techniques and biological recognition strategies.

癌症是最常见的威胁生命的疾病，也是全世界死亡率最高的疾病。癌症的早期诊断对其有效和成功的治疗起着至关重要的作用。传统的癌症筛查诊断方法成本高、耗时长，而且不适合重复筛查。然而，基于生物标志物的癌症诊断正在成为早期诊断、监测疾病进展和后续癌症治疗的最有希望的策略之一。这篇综述描述了电化学生物传感器的最新进展和改进，这些传感器设计用于使用不同的信号转导技术和生物识别策略检测各种癌症生物标志物。