Long Noncoding RNA CTD-2589M5.4 Inhibits Ovarian Cancer Cell Proliferation, Migration, and Invasion Via Downregulation of the Extracellular Matrix–Receptor Interaction Pathway,Cancer Biotherapy and Radiopharmaceuticals

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Long Noncoding RNA CTD-2589M5.4 Inhibits Ovarian Cancer Cell Proliferation, Migration, and Invasion Via Downregulation of the Extracellular Matrix–Receptor Interaction Pathway
Cancer Biotherapy and Radiopharmaceuticals ( IF 3.4 ) Pub Date : 2022-09-08 , DOI: 10.1089/cbr.2020.4429
Yuanyuan Gu _{1,

2} , Ke Huang ₁ , Min Zhang ₁ , Fang Teng ₁ , Lili Ge ₁ , Juan Zhou ₁ , Juan Xu ₁ , Xuemei Jia ₁

Affiliation

Background: The authors' previous study showed that the long noncoding RNA CTD-2589M5.4 was significantly upregulated in multidrug-resistant ovarian cancer cells. However, the role of CTD-2589M5.4 in the progression of ovarian cancer remains unclear. The purpose of this current study was to illuminate the biological function and possible mechanism of CTD-2589M5.4 in ovarian cancer development.

中文翻译：

长链非编码 RNA CTD-2589M5.4 通过下调细胞外基质-受体相互作用途径抑制卵巢癌细胞增殖、迁移和侵袭

背景：作者之前的研究表明，长链非编码 RNA CTD-2589M5.4 在多重耐药卵巢癌细胞中显着上调。然而，CTD-2589M5.4 在卵巢癌进展中的作用仍不清楚。本研究的目的是阐明 CTD-2589M5.4 在卵巢癌发展中的生物学功能和可能的机制。

更新日期：2022-09-09

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