The distance Wagner procedure of Farris (American Naturalist, 1972, 106, 645), in its original or random addition sequence form, is a rapid method of tree construction. The original formulation did not allow for refinement of tree hypotheses via common trajectory search operations (e.g. SPR, TBR). Here, the distance Wagner method is extended to allow for refinement of initial trees produced via the four-point condition (Mathematics and the Archeological and Historical Sciences, Edinburgh University Press, Edinburgh, 1974). The performance of the extended distance Wagner as a heuristic search procedure is evaluated with several unaligned sequences and combined source datasets within the parsimony framework. Distance Wagner both with and without refinement is shown to be a rapid and useful heuristic method to generate initial trees for further, character-based, analysis.

中文翻译：

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距离瓦格纳树细化作为基于字符的初始树构造的启发式方法

Farris 的距离 Wagner 程序（American Naturalist , 1972, 106, 645）以其原始或随机加法序列形式，是一种快速的树构造方法。最初的公式不允许通过常见的轨迹搜索操作（例如 SPR、TBR）来细化树假设。在这里，距离 Wagner 方法进行了扩展，以允许对通过四点条件（数学和考古学和历史科学）产生的初始树进行细化，爱丁堡大学出版社，爱丁堡，1974 年）。扩展距离 Wagner 作为启发式搜索过程的性能通过简约框架内的几个未对齐序列和组合源数据集进行评估。无论有没有细化，Distance Wagner 都被证明是一种快速且有用的启发式方法，可以生成初始树以进行进一步的基于字符的分析。