Biomedical implants with hierarchical hybrid surface morphologies have been highly pursued in dental and orthopedic fields. In this study, a scalelike micro/nano-textured structure was fabricated on plasma surface tantalum (Ta) alloyed Ti6Al4V substrate by removing the Ta deposition layer. The scalelike structure is composed of interconnected nano-step arrays within grains. The orientation of nano-steps arrays becomes more complicated, and the surface roughness increases with alloying time. The microhardness and wear resistance of this scalelike structure are improved due to the solid solution strengthening effect of Ta on Ti6Al4V substrate. Besides, in vitro assays demonstrate the viability and spreading ability of osteoblasts are well retained while the initial adhesion is greatly promoted with roughness increase. The improvements in alkaline phosphatase, collagen secretion and matrix mineralization indicate the enhanced osteogenic activities of this biomimetic structure. The excellent mechanical, biocompatibility and osteogenic activities of this scalelike structure highlight their promising potential in clinical practice.

具有分层混合表面形态的生物医学植入物在牙科和骨科领域受到高度追捧。在这项研究中，通过去除 Ta 沉积层，在等离子体表面钽 (Ta) 合金化 Ti6Al4V 衬底上制造了鳞片状微/纳米纹理结构。鳞片状结构由晶粒内相互连接的纳米阶梯阵列组成。纳米台阶阵列的取向变得更加复杂，表面粗糙度随着合金化时间的增加而增加。由于Ta在Ti6Al4V基体上的固溶强化作用，这种鳞片状结构的显微硬度和耐磨性得到提高。此外，体外试验表明成骨细胞的生存能力和扩散能力得到很好的保留，而初始粘附随着粗糙度的增加而大大提高。碱性磷酸酶、胶原蛋白分泌和基质矿化的改善表明这种仿生结构的成骨活性增强。这种鳞片状结构优异的机械、生物相容性和成骨活性突出了它们在临床实践中的潜力。