The immunocompetence and regeneration potential of the dental pulp and its surrounding apical tissues have been investigated extensively in the field of endodontics. While research on the role of non-coding RNAs in these tissues is still in its infancy, it is envisioned that improved understanding of the regulatory function of ncRNAs in pulpal and periapical immune response will help prevent or treat endodontic disease. Of particular importance is the role of these RNAs in regenerating the dentin-pulp complex. In this review, we highlight recent progress on the role of non-coding RNAs in the immune response to endodontic infection as well as the repair and regenerative response to injury.

牙髓及其周围根尖组织的免疫活性和再生潜力已在牙髓病学领域得到广泛研究。虽然关于非编码 RNA 在这些组织中的作用的研究仍处于起步阶段，但可以预见，提高对 ncRNA 在牙髓和根尖周免疫反应中的调节功能的理解将有助于预防或治疗牙髓疾病。特别重要的是这些 RNA 在再生牙本质-牙髓复合物中的作用。在这篇综述中，我们重点介绍了非编码 RNA 在对牙髓感染的免疫反应以及对损伤的修复和再生反应中的作用的最新进展。