Objectives The aim of our study is to present the effect of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in pregnancy and evaluate its impact on maternal and neonatal outcomes. Methods We retrospectively reviewed the medical records of all COVID-19 positive pregnant women who were admitted to “Alexandra” maternity hospital from March to December 2020 (n=40). The infection status was determined via real-time polymerase chain reaction (RT-PCR) of nasopharyngeal swab specimen. We documented the demographic features, clinical status, pregnancy characteristics and maternal and fetal outcomes. Results Forty COVID-19 positive pregnant women were admitted to our clinic during the study period. Mean maternal age was 27.6 years. Gestational age (GA) ranged from 10–42 weeks of pregnancy with mean GA calculated at 38 +3 weeks. Associated comorbidities included hypertension, hypothyroidism, epilepsy, hepatitis B and asthma. Thirty-five out of 40 women delivered within the study period. Cesarean section was performed in 57.1% of the cases. Most of the cases (87.5%) were asymptomatic while ventilation was required for only one patient. All neonates tested negative for SARS-CoV-2. Neither maternal nor neonatal deaths occurred. Conclusions In alignment to other studies, our data show that the course of coronavirus disease 2019 (COVID-19) during pregnancy in the majority of cases is mild and neonatal outcomes also appear favorable.

中文翻译：

---

Covid-19 和怀孕：三级妇产医院的经验

目的 我们研究的目的是展示严重急性呼吸系统综合症冠状病毒 2 (SARS-CoV-2) 感染对妊娠的影响，并评估其对母婴结局的影响。方法 我们回顾性审查了 2020 年 3 月至 12 月期间入住“亚历山德拉”妇产医院的所有 COVID-19 阳性孕妇的医疗记录（n=40）。通过鼻咽拭子标本的实时聚合酶链反应 (RT-PCR) 确定感染状态。我们记录了人口统计学特征、临床状态、妊娠特征以及母婴结局。结果 在研究期间，我们诊所收治了 40 名 COVID-19 阳性孕妇。平均产妇年龄为 27.6 岁。胎龄 (GA) 范围为怀孕 10-42 周，平均 GA 计算为 38 + 3 周。相关的合并症包括高血压、甲状腺功能减退、癫痫、乙型肝炎和哮喘。40 名妇女中有 35 名在研究期间分娩。57.1% 的病例进行了剖腹产。大多数病例 (87.5%) 没有症状，而只有一名患者需要通气。所有新生儿的 SARS-CoV-2 检测均呈阴性。没有发生孕产妇和新生儿死亡。结论 与其他研究一致，我们的数据显示，在大多数情况下，怀孕期间 2019 年冠状病毒病 (COVID-19) 的病程是轻微的，新生儿结局也似乎良好。5%) 没有症状，而只有一名患者需要通气。所有新生儿的 SARS-CoV-2 检测均呈阴性。没有发生孕产妇和新生儿死亡。结论 与其他研究一致，我们的数据显示，在大多数情况下，怀孕期间 2019 年冠状病毒病 (COVID-19) 的病程是轻微的，新生儿结局也似乎良好。5%) 没有症状，而只有一名患者需要通气。所有新生儿的 SARS-CoV-2 检测均呈阴性。没有发生孕产妇和新生儿死亡。结论 与其他研究一致，我们的数据显示，在大多数情况下，怀孕期间 2019 年冠状病毒病 (COVID-19) 的病程是轻微的，新生儿结局也似乎良好。