While the strong axial UO bonds confer high stability and inertness to UO₂²⁺, it has been shown that the axial oxo ligands can be eliminated or replaced in the gas-phase using collision-induced dissociation (CID) reactions. In this study, CID of the pentafluorobenzoate precursor ion [UO₂(O₂C–C₆F₅)]⁺ was used to produce the organo-uranyl ion [UO₂(C₆F₅)]⁺ by decarboxylation. Subsequent CID of [UO₂(C₆F₅)]⁺ created [UO₂(F)]⁺ by fluoride transfer and elimination of C₆F₄, rather than UO₂⁺ by elimination of pentafluorophenyl radical (as has been observed for similar species). Moreover, upon reaction of [UO₂(C₆F₅)]⁺ with H₂O, apparent substitution of OH for F to create [UO₃HC₆F₄]⁺ is favored over hydrolysis to produce [UO₂(OH)]⁺ and (neutral) C₆F₅H. Subsequent CID of [UO₃HC₆F₄]⁺ generates [UO₂(F)]⁺ and [OUF]⁺. When [OUF]⁺ is isolated to react with H₂O and O₂ in the ion trap, the principal product ions observed are [UO₂(F)]⁺ and [UO₂(OH)]⁺. Experiments conducted with labeled reagent suggest that reaction with H₂¹⁸O leads to exchange of the oxo ligand and incorporation of the ¹⁸O label into [OUF]⁺ while reaction with O₂ likely creates [UO₂(F)]⁺. Formation of [UO₂(OH)]⁺ from [OUF]⁺ is the result of a cascade of reactions, with initial formation of [UO₂(F)]⁺ by reaction with O₂, followed by hydrolysis to create the hydroxide species.

虽然强大的轴向 U O 键赋予 UO ₂ ²⁺高稳定性和惰性，但已经表明可以使用碰撞诱导解离 (CID) 反应在气相中消除或替换轴向氧配体。在本研究中，五氟苯甲酸盐母离子 [UO ₂ (O ₂ C–C ₆ F ₅ )] ^{+ 的}CID用于通过脱羧作用产生有机铀酰离子 [UO ₂ (C ₆ F ₅ )] ⁺。[UO ₂ (C ₆ F ₅ )] ⁺创建的 [UO ₂ (F)] 的后续 CID⁺通过氟化物转移和消除 C ₆ F ₄，而不是通过消除五氟苯基自由基来消除UO ₂ ⁺（如已观察到的类似物种）。此外，在 [UO ₂ (C ₆ F ₅ )] ⁺与 H ₂ O 反应时，用 OH 表观取代 F 生成 [UO ₃ HC ₆ F ₄ ] ⁺比水解生成 [UO ₂ (OH) ] ⁺和（中性）C ₆ F ₅ H. [UO ₃ HC _{6 的}后续 CIDF ₄ ] ⁺生成 [UO ₂ (F)] ⁺和 [OUF] ⁺。当[OUF] ⁺被隔离以与离子阱中的H ₂ O 和O ₂反应时，观察到的主要产物离子是[UO ₂ (F)] ⁺和[UO ₂ (OH)] ⁺。用标记试剂进行的实验表明，与 H ₂ ¹⁸ O 的反应导致氧代配体的交换和¹⁸ O 标记并入 [OUF] ⁺而与 O _{2 的}反应可能会产生 [UO ₂ (F)] ⁺. 从 [OUF] ⁺形成 [UO ₂ (OH)] ⁺是级联反应的结果，最初通过与 O ₂反应形成 [UO ₂ (F)] ⁺，然后水解产生氢氧化物物质.