Rhodesain is the generic name for the cathepsin L-like peptidase of Trypanosoma brucei rhodesiense. The term rhodesain was derived from the subspecies epithet rhodesiense which itself originated form Rhodesia, a historical region in southern Africa named after the 19th century British imperialist and white supremacist Cecil Rhodes. This tainting could be grounds for discontinuing the name, however, there are also scientific grounds. Specifically, protein sequence comparisons and frequency-based difference profiling reveal that rhodesain is essentially identical (99.87−98.44%) to the cathepsin L-like peptidases of both T. b. brucei and T. b. gambiense. Accordingly, and based on a previously proposed terminology for kinetoplastid C1 peptidases (Caffrey and Steverding, 2009), we suggest the use of the formal term, TbrCATL, to denote the cathepsin L-like peptidases of the T. brucei subspecies. The earlier and informal term, ‘brucipain’, could also be used.

Rhodesain是Trypanosoma brucei rhodesiense组织蛋白酶L样肽酶的总称。rhodesain 一词来源于亚种加词rhodesiense，它本身起源于罗得西亚，这是南部非洲的一个历史地区，以 19 世纪英国帝国主义和白人至上主义者塞西尔罗兹的名字命名。这种污染可能是停止使用该名称的理由，但是，也有科学依据。具体而言，蛋白质序列比较和基于频率的差异分析表明，罗地塞因与两种结核杆菌的组织蛋白酶 L 样肽酶基本相同 (99.87-98.44%) 。brucei和T. b. 冈比亚. 因此，基于先前提出的动质体 C1 肽酶术语（Caffrey 和 Steverding，2009），我们建议使用正式术语Tbr CATL 来表示布氏锥虫亚种的组织蛋白酶 L 样肽酶。也可以使用较早的非正式术语“brucipain”。