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Evaluation of Near-infrared Fluorescence-conjugated Peptides for Visualization of Human Epidermal Receptor 2-overexpressed Gastric Cancer.
Journal of Gastric Cancer ( IF 2.5 ) Pub Date : 2021-06-28 , DOI: 10.5230/jgc.2021.21.e18
Kyoungyun Jeong 1 , Seong-Ho Kong 2, 3 , Seong-Woo Bae 1 , Cho Rong Park 1, 4, 5 , Felix Berlth 6 , Jae Hwan Shin 7 , Yun-Sang Lee 1, 7 , Hyewon Youn 4, 5 , Eunhee Koo 1 , Yun-Suhk Suh 2, 3, 8 , Do Joong Park 1, 2, 3 , Hyuk-Joon Lee 1, 2, 3 , Han-Kwang Yang 1, 2, 3
Affiliation  

A near-infrared (NIR) fluorescence imaging is a promising tool for cancer-specific image guided surgery. Human epidermal receptor 2 (HER2) is one of the candidate markers for gastric cancer. In this study, we aimed to synthesize HER2-specific NIR fluorescence probes and evaluate their applicability in cancer-specific image-guided surgeries using an animal model.

中文翻译:

评价近红外荧光偶联肽对人表皮受体 2 过表达胃癌的可视化。

近红外 (NIR) 荧光成像是癌症特异性图像引导手术的有前途的工具。人表皮受体2(HER2)是胃癌的候选标志物之一。在这项研究中,我们旨在合成 HER2 特异性 NIR 荧光探针,并使用动物模型评估它们在癌症特异性图像引导手术中的适用性。
更新日期:2021-07-10
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