An amperometric biosensor for 1,2-dihydroxynaphthalene (DHN) and catechol (Cat) has been developed in order to monitor the biodegradaton of polycyclic aromatic hydrocarbons (PAHs). DHN is a common intermediary metabolite in naphthalene and phenanthrene degradation, while Cat is produced by further degradation. These compounds were detected by a biosensor modified with pyrroloquinoline quinone-dependent glucose dehydrogenase (PQQ-GDH). The biosensor was based on signal amplification by enzyme-catalyzed redox cycling and was able to detect DHN and Cat at very low concentrations down to 10⁻⁹ M. Since the anodic waves of DHN and Cat were well separated, simultaneous determinations of these compounds were possible. Although the current signal for DHN was reduced in repeated measurements due to the oxidative polymerization of DHN, it can be avoided when the concentration of DHN was sufficiently low (<1 μM).

为了监测多环芳烃 (PAH) 的生物降解，开发了一种用于 1,2-二羟基萘 (DHN) 和儿茶酚 (Cat) 的电流生物传感器。DHN是萘和菲降解中常见的中间代谢物，而Cat则是进一步降解产生的。这些化合物通过用吡咯并喹啉醌依赖性葡萄糖脱氢酶 (PQQ-GDH) 修饰的生物传感器进行检测。该生物传感器基于酶催化氧化还原循环的信号放大，能够检测低至 10 ^{-9 的}极低浓度的 DHN 和 CatM. 由于 DHN 和 Cat 的阳极波分离良好，因此可以同时测定这些化合物。虽然 DHN 的电流信号由于 DHN 的氧化聚合而在重复测量中降低，但当 DHN 的浓度足够低 (<1 μM) 时可以避免这种情况。