Significance: The use of the transscleral illumination approach has the potential to simplify the optical design of fundus cameras. In particular, this approach could allow the use of smaller and cheaper cameras that are easier to use by non-specialists, thereby facilitating a wider spread of eye disease screening programs. Aim: Our aim was to investigate the suitability of transscleral illumination in a fundus camera system. In particular, we explored the impact of the illumination spectrum and the eye pigmentation on the quality of the image. These factors have never been systematically investigated before in the literature on transscleral illumination. Approach: A fundus camera was constructed using transscleral illumination. We studied the influence of eye pigmentation and choice of illumination spectra on the image quality for a group of 10 individuals with varied skin pigmentation, ranging from pale white (North-European) to darkest brown (African). The influence of the light source spectrum on the image quality was assessed using wavelength filters. Results: There was a difference of a factor of 100 in the signal level of retinal images between individuals with low and high skin pigmentation. The image contrast was highest using illumination wavelengths of 500 to 600 nm. The illumination level can be adjusted to obtain high-quality images for highly pigmented eyes while keeping the system eye-safe. Conclusions: We have demonstrated that a fundus camera with transscleral illumination can provide high-quality images. However, the variations observed in scleral and retinal pigmentation in a practical setting require a system that must be able to adapt illumination and/or exposure to the individual patient.

中文翻译：

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照明光谱和眼睛色素沉着对使用经巩膜照明的眼底相机图像质量的影响

意义：使用经巩膜照明方法有可能简化眼底相机的光学设计。特别是，这种方法可以允许使用更小、更便宜的相机，这些相机更易于非专业人员使用，从而促进眼病筛查计划的更广泛传播。目的：我们的目的是研究眼底照相机系统中经巩膜照明的适用性。我们特别探讨了照明光谱和眼睛色素沉着对图像质量的影响。这些因素以前从未在有关经巩膜照明的文献中进行过系统研究。方法：使用经巩膜照明构建眼底照相机。我们研究了眼睛色素沉着和照明光谱的选择对具有不同皮肤色素沉着的 10 个人的图像质量的影响，范围从浅白色（北欧）到深棕色（非洲）。使用波长滤波器评估光源光谱对图像质量的影响。结果：低皮肤色素沉着和高皮肤色素沉着的个体之间视网膜图像的信号水平存在 100 倍的差异。使用 500 至 600 nm 的照明波长时，图像对比度最高。可以调整照度水平以获得高色素眼睛的高质量图像，同时保持系统的眼睛安全。结论：我们已经证明具有经巩膜照明的眼底照相机可以提供高质量的图像。然而，