Glioblastoma (GBM) is an aggressive primary CNS neoplasm with poor overall survival (OS) despite standard of care. On MRI, GBM is usually characterized by an enhancing portion (CET) (surgery target) and a nonenhancing surrounding (NET). Extent of resection is a long debated issue in GBM, with recent evidence suggesting that both CET and NET should be resected in <65 years old patients, regardless of other risk factors (i.e., molecular biomarkers). Our aim was to test a radiomic model for patient survival stratification in <65 years old patients, by analyzing MRI features of NET, to aid tumor resection.

中文翻译：

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预测生存的胶质母细胞瘤放射组学：周围非增强组织的扩散特征以选择广泛切除的患者

胶质母细胞瘤 (GBM) 是一种侵袭性原发性中枢神经系统肿瘤，尽管有标准的护理，但总生存期 (OS) 很差。在 MRI 上，GBM 通常以增强部分 (CET)（手术目标）和非增强周围 (NET) 为特征。切除范围在 GBM 中是一个长期争论的问题，最近的证据表明，无论其他危险因素（即分子生物标志物）如何，都应在 <65 岁的患者中切除 CET 和 NET。我们的目标是通过分析 NET 的 MRI 特征来测试 <65 岁患者的患者生存分层的放射组学模型，以帮助肿瘤切除。