The use of engineered phages offers a unique opportunity to improve on wild-type (WT) phages to generate ever more successful therapeutics to combat bacterial infections. Here, we discuss how phage engineering could be used to overcome some of the technical challenges of phage therapy, and suggest some areas in which more research will be crucial to the development of further novel phage therapeutics.

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工程噬菌体作为治疗剂的发展评论

工程化噬菌体的使用为改进野生型 (WT) 噬菌体提供了独特的机会，以产生更成功的治疗方法来对抗细菌感染。在这里，我们讨论了如何使用噬菌体工程来克服噬菌体疗法的一些技术挑战，并提出一些研究对于开发进一步的新型噬菌体疗法至关重要的领域。