Chalcones derivatized with 1-(2-quinolonyl)-1,2,3-triazoles were synthesized by reaction of 4-azido-2-quinolones with 1-phenyl-3-(4-propargyloxyphenyl)prop-2-en-1-one, or by aldol reaction of 4-{[1-(2-oxo-1,2-dihydroquinolin-4-yl)-1 H -1,2,3-triazol-4-yl]methoxy}benzaldehydes with acetophenone. Whereas, chalcones bearing two 1-(2-quinolonyl)-1,2,3-triazoles were synthesized by reaction of 1,3-bis(4-propargyloxyphenyl)prop-2-en-1-one with 4-azido-2-quinolones, or by aldol condensation between 4-{4-[(4-acetylphenoxy)methyl]-1 H -1,2,3-triazol-1-yl}quinolin-2(1 H )-ones and 4-{[1-(2-oxo-1,2-dihydroquinolin-4-yl)-1 H -1,2,3-triazol-4-yl]methoxy}benzaldehydes.

中文翻译：

---

用两个 1-(2-quinolon-4-yl)-1,2,3-三唑衍生的查耳酮的高效点击合成

由 1-(2-quinolonyl)-1,2,3-triazoles 衍生的查尔酮是通过 4-azido-2-quinolones 与 1-phenyl-3-(4-propargyloxyphenyl)prop-2-en-1- 反应合成的一种，或通过 4-{[1-(2-oxo-1,2-dihydroquinolin-4-yl)-1 H -1,2,3-triazol-4-yl] 甲氧基}苯甲醛与苯乙酮的羟醛反应。而带有两个 1-(2-quinolonyl)-1,2,3-triazoles 的查耳酮是通过 1,3-bis(4-propargyloxyphenyl)prop-2-en-1-one 与 4-azido-2 反应合成的-喹诺酮类，或通过 4-{4-[(4-乙酰苯氧基)甲基]-1 H -1,2,3-三唑-1-基}喹啉-2(1 H)-酮和 4-{ [1-(2-oxo-1,2-dihydroquinolin-4-yl)-1 H -1,2,3-triazol-4-yl] 甲氧基}苯甲醛。