Abstract

Five previously undescribed guanacastane diterpenoids, namely psathyrellins A–E (1–5), were obtained from cultures of the mushroom Psathyrella candolleana. Their structures with absolute configurations were elucidated by extensive spectroscopic methods. Compounds 1–3 showed antibacterial activity against four strains with MIC values in a range of 16–128 μg/mL.

Graphic Abstract

中文翻译：

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Psathyrellins A–E，来自蘑菇 Psathyrella candolleana 的抗菌胍那卡烷二萜

摘要

五个以前未描述guanacastane二萜类化合物，即psathyrellins A-E（1 - 5），从该蘑菇的培养物中获得Psathyrella candolleana。通过广泛的光谱方法阐明了它们具有绝对构型的结构。化合物1 - 3显示抗菌活性对四种菌株与MIC值的范围16-128微克/毫升的。

图形摘要