The study examined whether cardiovascular responses to psychological stress tests predict future anxiety and depression scores 40-months later. Hemodynamic measures were obtained from 102 healthy adults before, during and after mental arithmetic, a speech task, and a cold pressor task. The 14-item Hospital Anxiety and Depression Scale was administered at initial testing and at 40-months follow-up. At initial testing analyses revealed that high anxiety symptoms were characterized by blunted cardiovascular reactions to acute mental stress, particularly mental arithmetic. Furthermore, after adjustment for baseline blood pressure (BP), baseline anxiety levels and traditional risk factors, attenuated systolic BP responses to mental arithmetic were associated with future anxiety levels (ΔR2 = .055). These findings suggest that blunted cardiovascular reactions to stress may be an independent risk factor for future anxiety levels.

中文翻译：

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迟钝的心血管反应是负面健康结果的预测指标：一项前瞻性队列研究

该研究检查了心血管对心理压力测试的反应是否能预测 40 个月后未来的焦虑和抑郁评分。在心算、言语任务和冷加压任务之前、期间和之后，从 102 名健康成年人中获得了血流动力学测量值。14 项医院焦虑和抑郁量表在初始测试和 40 个月的随访中进行。最初的测试分析显示，高度焦虑症状的特征是对急性精神压力的心血管反应迟钝，尤其是心算。此外，在调整基线血压 (BP)、基线焦虑水平和传统危险因素后，心算收缩压反应减弱与未来的焦虑水平相关 (ΔR2 = .055)。