This study involves the mitochondrial-reticular network, which is functionally integrated into the processes that provide energy to all systems of an organism as an open, dynamic, self-regulatory organization involved in the energy homeostasis of the cell under the control of AMP-activated protein kinase as the main energy indicator. The mitochondrial-reticular network is regulated by at least three multidirectional energy vectors, that is, mitochondrial fission and fusion, and mitochondrial apoptosis mechanisms. A kinetic mathematical model of the mitochondrial-reticular network function is proposed. The search for effective strategies for the functioning of mitochondrial-reticular network is resolved into constrained optimization through the use of the Lagrange multiplier.

这项研究涉及线粒体 - 网状网络，它在功能上整合到为生物体的所有系统提供能量的过程中，作为一个开放的、动态的、自我调节的组织，在 AMP 激活的控制下参与细胞的能量稳态蛋白激酶作为主要的能量指标。线粒体-网状网络至少受三个多向能量载体的调控，即线粒体裂变和融合，以及线粒体凋亡机制。提出了线粒体-网状网络函数的动力学数学模型。通过使用拉格朗日乘数，寻找线粒体网状网络功能的有效策略被解析为约束优化。