Introduction: Graph theory has been applied to study the pathophysiology of multiple sclerosis (MS) since it provides global and focal measures of brain network properties that are affected by MS. Typically, the connection strength and, consequently, the network properties are computed by counting the number of streamlines (NOS) connecting couples of gray matter regions. However, recent studies have shown that this method is not quantitative.

中文翻译：

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多发性硬化症中的微结构加权连接组学

简介：图论已被应用于研究多发性硬化症 (MS) 的病理生理学，因为它提供了受 MS 影响的大脑网络特性的全局和焦点测量。通常，连接强度和网络属性是通过计算连接灰质区域对的流线 (NOS) 的数量来计算的。然而，最近的研究表明，这种方法不是定量的。