The coming years are expected to bring rapid changes in the nanotechnology regulatory landscape, with the establishment of a new framework for nano-risk governance, in silico approaches for characterisation and risk assessment of nanomaterials, and novel procedures for the early identification and management of nanomaterial risks. In this context, Safe(r)-by-Design (SbD) emerges as a powerful preventive approach to support the development of safe and sustainable (SSbD) nanotechnology-based products and processes throughout the life cycle. This paper summarises the work undertaken to develop a blueprint for the deployment and operation of a permanent European Centre of collaborating laboratories and research organisations supporting safe innovation in nanotechnologies. The proposed entity, referred to as “the Centre”, will establish a ‘one-stop shop’ for nanosafety-related services and a central contact point for addressing stakeholder questions about nanosafety. Its operation will rely on significant business, legal and market knowledge, as well as other tools developed and acquired through the EU-funded EC4SafeNano project and subsequent ongoing activities. The proposed blueprint adopts a demand-driven service update scheme to allow the necessary vigilance and flexibility to identify opportunities and adjust its activities and services in the rapidly evolving regulatory and nano risk governance landscape.

The proposed Centre will play a major role as a conduit to transfer scientific knowledge between the research and commercial laboratories or consultants able to provide high quality nanosafety services, and the end-users of such services (e.g., industry, SMEs, consultancy firms, and regulatory authorities). The Centre will harmonise service provision, and bring novel risk assessment and management approaches, e.g. in silico methodologies, closer to practice, notably through SbD/SSbD, and decisively support safe and sustainable innovation of industrial production in the nanotechnology industry according to the European Chemicals Strategy for Sustainability.

随着纳米风险治理新框架的建立、纳米材料表征和风险评估的计算机方法以及纳米材料早期识别和管理的新程序的建立，预计未来几年将带来纳米技术监管格局的快速变化风险。在这种情况下，Safe(r)-by-Design (SbD) 成为一种强有力的预防方法，可在整个生命周期内支持基于纳米技术的安全和可持续 (SSbD) 产品和工艺的开发。本文总结了为部署和运营支持纳米技术安全创新的合作实验室和研究组织的欧洲常设中心制定蓝图而开展的工作。提议的实体，称为“中心”，将为纳米安全相关服务建立一个“一站式商店”，并为解决利益相关者有关纳米安全的问题建立一个中央联络点。其运营将依赖于重要的商业、法律和市场知识，以及通过欧盟资助的 EC4SafeNano 项目和后续正在进行的活动开发和获得的其他工具。拟议的蓝图采用需求驱动的服务更新计划，以允许必要的警惕性和灵活性，以在快速发展的监管和纳米风险治理环境中识别机会并调整其活动和服务。

拟建中心将发挥重要作用，作为研究和能够提供高质量纳米安全服务的商业实验室或顾问以及此类服务的最终用户（例如，工业、中小企业、咨询公司和监管部门）。该中心将协调服务提供，并带来新的风险评估和管理方法，例如计算机方法，更接近实践，特别是通过 SbD/SSbD，并根据欧洲化学品的规定，果断支持纳米技术行业工业生产的安全和可持续创新可持续发展战略。