Triterpenes are a wide and important group of compounds that have several promising pharmacological properties, such as hepatoprotective, anti-inflammatory, anti-HIV, antioxidant, or anticancer activities. Such potent substances can be successfully incorporated in more complex chemical systems e.g. codrugs or pro-drugs that have a better pharmacological profile. The codrug is connected with a drug formation pathway to chemically cohere at least two drug molecules to improve positive therapeutic efficiency or decrease side effects. The codrug can be cleaved in the organism to generate effective compounds previously used as substrates. This article presents an overview of codrugs that consist of pentacyclic triterpene moiety that is chosen as a basic codrug moiety due to their wide range of vital activities and another drug molecule fragment. It was found that triterpenoid codrugs are characterized by a wide range of biological activities. However, most of them have anticancer potency.

三萜类化合物是一组广泛而重要的化合物，具有多种有希望的药理特性，例如保肝、抗炎、抗 HIV、抗氧化或抗癌活性。此类强效物质可以成功地结合到更复杂的化学系统中，例如具有更好药理学特征的共药或前药。联合药物与药物形成途径相连，以化学方式凝聚至少两个药物分子，以提高积极的治疗效率或减少副作用。协同药物可以在生物体中裂解以产生以前用作底物的有效化合物。本文概述了由五环三萜部分组成的共药概述，五环三萜部分因其广泛的生命活性而被选为基本共药部分和另一种药物分子片段。发现三萜类共药具有广泛的生物活性。然而，它们中的大多数具有抗癌效力。