The crystal structure of daclatasvir dihydrochloride Form N-2 (Daklinza®) has been refined using synchrotron X-ray powder diffraction data and optimized using density functional theory techniques. Daclatasvir dihydrochloride, Form N-2, crystallizes in space group P1 (#1) with a = 7.54808 (15), b = 9.5566 (5), c = 16.2641 (11) Å, α = 74.0642 (24), β = 84.0026 (13), γ = 70.6322 (5)°, V = 1064.150(11) Å3, and Z = 1. The hydrogen bonds were identified and quantified. Strong N–H⋯Cl hydrogen bonds link the cations and anions in chains along the a-axis. The powder pattern has been submitted to ICDD® for inclusion in the Powder Diffraction File™ (PDF®).

中文翻译：

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daclatasvir dihydrochloride Form N-2 (Daklinza®), C40H52N8O6Cl2 的粉末 X 射线衍射

daclatasvir dihydrochloride Form N-2 (Daklinza®) 的晶体结构已使用同步加速器 X 射线粉末衍射数据进行了细化，并使用密度泛函理论技术进行了优化。Daclatasvir dihydrochloride，N-2 型，在空间群中结晶磷1 (#1) 与一种= 7.54808 (15),b= 9.5566 (5),C= 16.2641 (11) 埃，α= 74.0642 (24),β= 84.0026 (13),γ= 70.6322 (5)°,五= 1064.150(11) Å3， 和Z= 1. 氢键被识别和量化。强 N-H⋯Cl 氢键将阳离子和阴离子沿链连接起来一种-轴。粉末图案已提交给 ICDD® 以包含在 Powder Diffraction File™ (PDF®) 中。