Microwave irradiated free radical synthesis of polyacrylamide-flax seed mucilage graft copolymeric hydrogel (PFLSM-g-PAM-cl-MBA) was evaluated for pH sensitivity at pH 2, 8 with maximum swellability at pH 7.4.The analytical characterizations of the optimized grade G6 was done using FTIR spectroscopy, 13C-NMR, TGA, XRD which indicated that grafting of acrylamide was successfully done on flax seed mucilage (PFLSM). The elemental composition also indicated successful grafting of acrylamide on flax seed mucilage. The electrokinetic potential of the G6 indicated it to be a good colloid stabilizer when compared to PFLSM. The surface morphology of G6 as observed by scanning electron microscope (SEM) and field emission scanning electron microscope (FESEM) indicated porous surface, whereas PFLSM as observed by SEM showed smooth topography. The inserted G6 in mice model showed satisfactory tissue growth with evidence of tissue compatibility as observed under Field emission scanning electron microscopy (FESEM).Histopathology studies of local tissue showed sufficient fibroblast and collagen growth indicating PFLSM-g-PAM-cl-MBA to be a promising pH-sensitive novel material for tissue proliferation as polymeric scaffold.

微波辐照自由基合成聚丙烯酰胺-亚麻籽粘液接枝共聚物水凝胶 (PFLSM-g-PAM-cl-MBA) 在 pH 2、8 时的 pH 敏感性进行了评估，在 pH 7.4 时具有最大溶胀性。 优化级 G6 的分析表征使用 FTIR 光谱、13C-NMR、TGA、XRD 完成，表明丙烯酰胺在亚麻籽粘液 (PFLSM) 上成功接枝。元素组成也表明丙烯酰胺在亚麻籽粘液上成功接枝。与 PFLSM 相比，G6 的电动势表明它是一种良好的胶体稳定剂。通过扫描电子显微镜 (SEM) 和场发射扫描电子显微镜 (FESEM) 观察到的 G6 的表面形态表明多孔表面，而通过 SEM 观察到的 PFLSM 显示出光滑的形貌。