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Ethics and regulatory considerations for the clinical translation of somatic cell human epigenetic editing
Stem Cell Reports ( IF 5.9 ) Pub Date : 2021-07-01 , DOI: 10.1016/j.stemcr.2021.06.004
Nikolajs Zeps 1 , Tamra Lysaght 2 , Ruth Chadwick 3 , Alexandre Erler 4 , Roger Foo 5 , Simona Giordano 6 , Poh San Lai 7 , G Owen Schaefer 2 , Vicki Xafis 2 , Wei Leong Chew 8 , Jeremy Sugarman 9
Affiliation  

Altering the human epigenome with gene-editing technology in attempt to treat a variety of diseases and conditions seems scientifically feasible. We explore some of the ethical and regulatory issues related to the clinical translation of human epigenetic editing arguing that such approaches should be considered akin to somatic therapies.



中文翻译:

体细胞人类表观遗传编辑临床翻译的伦理和监管考虑

用基因编辑技术改变人类表观基因组以尝试治疗各种疾病和病症似乎在科学上是可行的。我们探讨了与人类表观遗传编辑的临床翻译相关的一些伦理和监管问题,认为此类方法应被视为类似于体细胞疗法。

更新日期:2021-07-13
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