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Native joint infections caused by Parvimonas micra
Anaerobe ( IF 2.3 ) Pub Date : 2021-07-01 , DOI: 10.1016/j.anaerobe.2021.102412
Patrick M Ryan 1 , Caleb P Shin 2
Affiliation  

Parvimonas micra is an anaerobic, fastidious, gram positive organism commonly found in the oral cavity and gastrointestinal tract. It has been increasingly reported as the cause of septic arthritis of native joints, often times with delayed diagnosis leading to increased morbidity. Risk factors include immunosuppression, inflammation of the joint, and recent dental procedures or infections. It has been a historically difficult organism to culture. However, the development of and increasing use of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) has led to increased identification of P. micra. Common antibiotic susceptibilities, as well as data regarding susceptibilities in specific situations, have been reported, but susceptibility testing is required in all cases. Common treatments include clindamycin, penicillin, and metronidazole for six to ten weeks.



中文翻译:

Parvimonas micra 引起的自然关节感染

Parvimonas micra是一种厌氧、挑剔、革兰氏阳性微生物,常见于口腔和胃肠道。它越来越多地被报道为天然关节脓毒性关节炎的原因,通常诊断延迟导致发病率增加。风险因素包括免疫抑制、关节炎症以及近期的牙科手术或感染。它在历史上一直是一种难以培养的有机体。然而,基质辅助激光解吸/电离飞行时间质谱 (MALDI-TOF-MS) 的发展和使用的增加导致对P. micra的鉴定增加. 已经报道了常见的抗生素敏感性以及特定情况下的敏感性数据,但在所有情况下都需要进行敏感性测试。常见的治疗方法包括克林霉素、青霉素和甲硝唑,持续 6 到 10 周。

更新日期:2021-07-16
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