Abstract

Rhythmic light stimulation can alter the electrical activity of the human and animal brain. Moreover, the brain response to certain flicker frequencies significantly exceeds the responses to neighboring frequencies. This phenomenon is thought to be related with the effect of resonance, as evidenced by the coincidence of one of the maxima in the profile of the response to flashes with the frequency of the alpha rhythm. However, other frequencies that cause an increased response to flashes are not reflected in electroencephalogram (EEG) as dominant oscillations. The goal of this study was to reveal the relationship between local maxima in the profile of the responses to flashes of different frequencies and dominant brain oscillations recorded in electrocorticogram (ECoG) of rhesus monkeys without stimulation. The study was carried out on four male rhesus monkeys Macaca mulatta. In three animals, peak responses were elicited by flickers at 8 and 16 Hz, while one monkey showed the second peak in the 22–30 Hz range. The first maximum (8–10 Hz) in the profile of the response to rhythmic photostimulation coincided with the dominant rhythm recorded in the occipital and parietal regions at rest. The second maximum at 16 Hz coincided with the dominant ECoG rhythm in one of the primates when it was in the state of emotional arousal, which may account for the resonant origin of the increase in responses in this frequency range. The data obtained indicate that dominant brain rhythms, including latent rhythms revealed only by rhythmic photostimulation, can coincide in frequency in monkeys and humans. The mechanisms behind the selective sensitivity of neural networks to different frequencies of photostimulation are discussed.

中文翻译：

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恒河猴猕猴脑节律的电生理研究

摘要

有节奏的光刺激可以改变人和动物大脑的电活动。此外，大脑对某些闪烁频率的反应明显超过对相邻频率的反应。这种现象被认为与共振效应有关，正如对闪光的响应曲线中的最大值之一与 alpha 节奏频率的重合所证明的那样。然而，导致对闪光的反应增加的其他频率在脑电图 (EEG) 中没有反映为主要振荡。这项研究的目的是揭示对不同频率闪光的反应曲线中的局部最大值与没有刺激的恒河猴皮层电图 (ECoG) 中记录的主要脑振荡之间的关系。猕猴. 在三只动物中，峰值响应由 8 和 16 Hz 的闪烁引起，而一只猴子在 22-30 Hz 范围内显示第二个峰值。对节律性光刺激的反应曲线中的第一个最大值 (8-10 Hz) 与在休息时枕叶和顶叶区域记录的主导节律一致。16 Hz 处的第二个最大值与其中一只灵长类动物处于情绪唤醒状态时的主要 ECoG 节律一致，这可能是该频率范围内响应增加的共振起源。获得的数据表明，猴子和人类的主要脑节律，包括仅通过有节奏的光刺激揭示的潜在节律，在频率上可能一致。讨论了神经网络对不同频率光刺激的选择性敏感性背后的机制。