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Cerebral palsy in Canadian Indigenous children
Developmental Medicine & Child Neurology ( IF 3.8 ) Pub Date : 2020-12-13 , DOI: 10.1111/dmcn.14776
Anjellica Chen 1 , Sasha Dyck Holzinger 2 , Maryam Oskoui 3, 4 , Michael Shevell 3, 4 , John Andersen , David Buckley , Darcy Fehlings , Lee Burkholder , Adam Kirton , Louise Koclas , Nicole Pigeon , Esias Van Rensburg , Jordan Sheriko , Ellen Wood ,
Affiliation  

AIM To determine whether inequities in health outcomes for Indigenous Canadians are also present in cerebral palsy (CP) by comparing CP profiles between Indigenous and non-Indigenous children. METHOD Using the Canadian Cerebral Palsy Registry, we conducted a cross-sectional study. CP motor subtype, gross motor severity, comorbidities, perinatal adversity, preterm birth, and parental education were compared between 94 Indigenous (53 males, 41 females) and 1555 non-Indigenous (891 males, 664 females) children (all >5y). Multivariate analysis was done to analyze adverse CP factors, defined as CP gross motor severity and comorbidities. CP etiologies, either prenatal/perinatal or postnatal, were also compared. RESULTS Indigenous children with CP have higher odds of having low parental education (odds ratio [OR] 6.15, 95% confidence interval [CI] 3.36-11.3) and comorbidities (OR 4.46, 95% CI 1.62-12.3), especially cognitive (OR 4.52, 95% CI 2.27-9.05), communication (OR 2.66, 95% CI 1.54-4.61), and feeding (OR 2.25, 95% CI 1.33-3.83) impairment. Indigenous children also have higher CP gross motor severity (p=0.03). Indigenous children are also more likely to have non-accidental head injury (n=4; OR 8.18, 95% CI 1.86-36.0) as the cause of their postnatal CP. INTERPRETATION Indigenous populations have worse health outcomes as a result of intergenerational impacts of colonization. Our study shows that Indigenous children with CP have increased comorbidities and higher CP gross motor severity, reinforcing the need for a multidisciplinary approach to management. Furthermore, targeted prevention programs against preventable causes of CP, such as non-accidental head injury, may be beneficial.

中文翻译:

加拿大土著儿童的脑瘫

目的 通过比较原住民和非原住民儿童的脑瘫 (CP) 情况,确定加拿大原住民健康结果的不平等是否也存在于脑瘫 (CP) 中。方法 使用加拿大脑瘫登记处,我们进行了一项横断面研究。对 94 名土著(53 名男性,41 名女性)和 1555 名非土著(891 名男性,664 名女性)儿童(均 > 5 岁)的 CP 运动亚型、大运动严重程度、合并症、围产期逆境、早产和父母教育进行了比较。进行多变量分析以分析不良 CP 因素,定义为 CP 粗大运动严重程度和合并症。还比较了产前/围产期或产后 CP 的病因。结果 患有 CP 的土著儿童父母受教育程度低的几率更高(几率 [OR] 6.15,95% 置信区间 [CI] 3。36-11.3) 和合并症 (OR 4.46, 95% CI 1.62-12.3),尤其是认知 (OR 4.52, 95% CI 2.27-9.05)、交流 (OR 2.66, 95% CI 1.54-4.61) 和喂养 (OR 4.52, 95% CI 1.54-4.61)。 , 95% CI 1.33-3.83) 减值。土著儿童的 CP 粗大运动严重程度也更高(p=0.03)。土著儿童也更有可能将非意外头部损伤(n=4;OR 8.18,95% CI 1.86-36.0)作为其产后脑瘫的原因。解释 由于殖民化的代际影响,土著居民的健康状况更差。我们的研究表明,患有 CP 的土著儿童的合并症增加,CP 粗大运动严重程度更高,这加强了对多学科管理方法的需求。此外,针对 CP 可预防原因(例如非意外头部损伤)的有针对性的预防计划可能是有益的。3) 和合并症(OR 4.46,95% CI 1.62-12.3),尤其是认知(OR 4.52,95% CI 2.27-9.05)、交流(OR 2.66,95% CI 1.54-4.61)和喂养(OR 2.25,95% CI 2.27-9.05) % CI 1.33-3.83) 减值。土著儿童的 CP 粗大运动严重程度也更高(p=0.03)。土著儿童也更有可能将非意外头部损伤(n=4;OR 8.18,95% CI 1.86-36.0)作为其产后脑瘫的原因。解释 由于殖民化的代际影响,土著居民的健康状况更差。我们的研究表明,患有 CP 的土著儿童的合并症增加,CP 粗大运动严重程度更高,这加强了对多学科管理方法的需求。此外,针对 CP 可预防原因(例如非意外头部损伤)的有针对性的预防计划可能是有益的。3) 和合并症(OR 4.46,95% CI 1.62-12.3),尤其是认知(OR 4.52,95% CI 2.27-9.05)、交流(OR 2.66,95% CI 1.54-4.61)和喂养(OR 2.25,95% CI 2.27-9.05) % CI 1.33-3.83) 减值。土著儿童的 CP 粗大运动严重程度也更高(p=0.03)。土著儿童也更有可能将非意外头部损伤(n=4;OR 8.18,95% CI 1.86-36.0)作为其产后脑瘫的原因。解释 由于殖民化的代际影响,土著居民的健康状况更差。我们的研究表明,患有 CP 的土著儿童的合并症增加,CP 粗大运动严重程度更高,这加强了对多学科管理方法的需求。此外,针对 CP 可预防原因(例如非意外头部损伤)的有针对性的预防计划可能是有益的。
更新日期:2020-12-13
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